Over 1.7 million cases were reported to the CDC in 2018, with an increase to over 1.8 million reported cases in 2019. However, actual annual chlamydia cases are estimated to be closer to 2.86 million.
Chlamydia infections were estimated to have a direct medical cost to the US healthcare system of $691 million in 2018. However, this direct medical cost is far lower than the total cost associated with chlamydia, as it does not include costs associated with lost productivity, other non-medical costs, and STI prevention.